SJ25C1 Fab in complex with soluble CD19
He C, Mansilla-Soto J, Khanra N, Hamieh M, Bustos V, Paquette AJ, Garcia Angus A, Shore DM, Rice WJ, Khelashvili G, Sadelain M, Meyerson JR
Science immunology (2023) 8 [ Pubmed: 36867678 DOI: 10.1126/sciimmunol.adf1426 ]
Image sets:
FMC63 scFv in complex with soluble CD19
He C, Mansilla-Soto J, Khanra N, Hamieh M, Bustos V, Paquette AJ, Garcia Angus A, Shore DM, Rice WJ, Khelashvili G, Sadelain M, Meyerson JR
Science immunology (2023) 8 [ Pubmed: 36867678 DOI: 10.1126/sciimmunol.adf1426 ]
Image sets:
FMC63 scFv in complex with soluble CD19
Resolution: 3.05 Å
EM Method: Single-particle
Fitted PDBs: 7urv
Q-score: 0.522
He C, Mansilla-Soto J, Khanra N, Hamieh M, Bustos V, Paquette AJ, Garcia Angus A, Shore DM, Rice WJ, Khelashvili G, Sadelain M, Meyerson JR
Sci Immunol (2023) 8 pp. eadf1426-eadf1426 [ Pubmed: 36867678 DOI: doi:10.1126/sciimmunol.adf1426 ]
- Fmc63 single-chain variable fragment (25 kDa, Protein from Mus musculus)
- Fmc63 single-chain variable fragment (Complex from Mus musculus)
- B-lymphocyte antigen cd19 (Complex from Homo sapiens)
- B-lymphocyte antigen cd19 (28 kDa, Protein from Homo sapiens)
- Fmc63 scfv in complex with soluble cd19 (Complex)
SJ25C1 Fab in complex with soluble CD19
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7urx
Q-score: 0.466
He C, Mansilla-Soto J, Khanra N, Hamieh M, Bustos V, Paquette AJ, Garcia Angus A, Shore DM, Rice WJ, Khelashvili G, Sadelain M, Meyerson JR
Sci Immunol (2023) 8 pp. eadf1426-eadf1426 [ Pubmed: 36867678 DOI: doi:10.1126/sciimmunol.adf1426 ]
- B-lymphocyte antigen cd19 (30 kDa, Protein from Homo sapiens)
- Sj25c1 fab heavy chain (27 kDa, Protein from Mus musculus)
- Sj25c1 fab light chain (25 kDa, Protein from Mus musculus)
- B-lymphocyte antigen cd19 (Complex from Homo sapiens)
- Sj25c1 fab light chain, sj25c1 fab heavy chain (Complex from Mus musculus)
- Sj25c1 fab in complex with soluble cd19 (Complex)
sd1.040 Fab in complex with SARS-CoV-2 Spike 2P glycoprotein
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 8d48
Q-score: 0.449
Bianchini F, Crivelli V, Abernathy ME, Guerra C, Palus M, Muri J, Marcotte H, Piralla A, Pedotti M, De Gasparo R, Simonelli L, Matkovic M, Toscano C, Biggiogero M, Calvaruso V, Svoboda P, Cervantes Rincon T, Fava T, Podesvova L, Shanbhag AA, Celoria A, Sgrignani J, Stefanik M, Honig V, Pranclova V, Michalcikova T, Prochazka J, Guerrini G, Mehn D, Ciabattini A, Abolhassani H, Jarrossay D, Uguccioni M, Medaglini D, Pan-Hammarstrom Q, Calzolai L, Fernandez D, Baldanti F, Franzetti-Pellanda A, Garzoni C, Sedlacek R, Ruzek D, Varani L, Cavalli A, Barnes CO, Robbiani DF
Sci Immunol (2023) 8 pp. eade0958-eade0958 [ Pubmed: 36701425 DOI: doi:10.1126/sciimmunol.ade0958 ]
- Sd1.040 fab heavy chain (24 kDa, Protein from Homo sapiens)
- Spike glycoprotein (139 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Sd1.040 fab in complex with sars-cov-2 spike 2p (79 kDa, Complex)
- Sd1.040 fab heavy chain, sd1.040 fab light chain (Complex from Homo sapiens)
- Spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Sd1.040 fab light chain (24 kDa, Protein from Homo sapiens)
Structure of the SARS-CoV-2 spike glycoprotein S2 subunit
Resolution: 3.67 Å
EM Method: Single-particle
Fitted PDBs: 8dya
Q-score: 0.382
Bowen JE, Park YJ, Stewart C, Brown JT, Sharkey WK, Walls AC, Joshi A, Sprouse KR, McCallum M, Tortorici MA, Franko NM, Logue JK, Mazzitelli IG, Nguyen AW, Silva RP, Huang Y, Low JS, Jerak J, Tiles SW, Ahmed K, Shariq A, Dan JM, Zhang Z, Weiskopf D, Sette A, Snell G, Posavad CM, Iqbal NT, Geffner J, Bandera A, Gori A, Sallusto F, Maynard JA, Crotty S, Van Voorhis WC, Simmerling C, Grifantini R, Chu HY, Corti D, Veesler D
Sci Immunol (2022) 7 pp. eadf1421-eadf1421 [ Pubmed: 36356052 DOI: doi:10.1126/sciimmunol.adf1421 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Spike glycoprotein (68 kDa, Protein from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 spike glycoprotein s2 subunit (Complex from Severe acute respiratory syndrome coronavirus 2)
- Sars-cov-2 spike s2 subunit (Complex from Severe acute respiratory syndrome coronavirus 2)
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 7upw
Q-score: 0.464
Luo S, Zhang J, Kreutzberger AJB, Eaton A, Edwards RJ, Jing C, Dai HQ, Sempowski GD, Cronin K, Parks R, Ye AY, Mansouri K, Barr M, Pishesha N, Williams AC, Vieira Francisco L, Saminathan A, Peng H, Batra H, Bellusci L, Khurana S, Alam SM, Montefiori DC, Saunders KO, Tian M, Ploegh H, Kirchhausen T, Chen B, Haynes BF, Alt FW
Sci Immunol (2022) 7 pp. eadd5446-eadd5446 [ Pubmed: 35951767 DOI: doi:10.1126/sciimmunol.add5446 ]
- Three rbd-down state of sars-cov-2 d614g spike in complex with the sp1-77 neutralizing antibody fab fragment (650 kDa, Complex)
- Sp1-77 fab heavy chain, sp1-77 fab light chain (Complex from Homo sapiens)
- Spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus)
- Sp1-77 fab heavy chain (49 kDa, Protein from Homo sapiens)
- Sp1-77 fab light chain (23 kDa, Protein from Homo sapiens)
- Spike glycoprotein (144 kDa, Protein from Severe acute respiratory syndrome coronavirus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7upx
Q-score: 0.513
Luo S, Zhang J, Kreutzberger AJB, Eaton A, Edwards RJ, Jing C, Dai HQ, Sempowski GD, Cronin K, Parks R, Ye AY, Mansouri K, Barr M, Pishesha N, Williams AC, Vieira Francisco L, Saminathan A, Peng H, Batra H, Bellusci L, Khurana S, Alam SM, Montefiori DC, Saunders KO, Tian M, Ploegh H, Kirchhausen T, Chen B, Haynes BF, Alt FW
Sci Immunol (2022) 7 pp. eadd5446-eadd5446 [ Pubmed: 35951767 DOI: doi:10.1126/sciimmunol.add5446 ]
- Three rbd-down state of sars-cov-2 d614g spike in complex with the sp1-77 neutralizing antibody fab fragment (local refinement of the rbd and fab variable domains) (6 MDa, Complex)
- Sp1-77 fab heavy chain, sp1-77 fab light chain (Complex from Homo sapiens)
- Spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus 2)
- Sp1-77 fab heavy chain (49 kDa, Protein from Homo sapiens)
- Sp1-77 fab light chain (23 kDa, Protein from Homo sapiens)
- Spike glycoprotein (144 kDa, Protein from Severe acute respiratory syndrome coronavirus)
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7upy
Q-score: 0.384
Luo S, Zhang J, Kreutzberger AJB, Eaton A, Edwards RJ, Jing C, Dai HQ, Sempowski GD, Cronin K, Parks R, Ye AY, Mansouri K, Barr M, Pishesha N, Williams AC, Vieira Francisco L, Saminathan A, Peng H, Batra H, Bellusci L, Khurana S, Alam SM, Montefiori DC, Saunders KO, Tian M, Ploegh H, Kirchhausen T, Chen B, Haynes BF, Alt FW
Sci Immunol (2022) 7 pp. eadd5446-eadd5446 [ Pubmed: 35951767 DOI: doi:10.1126/sciimmunol.add5446 ]
- Sp1-77 fab heavy chain, sp1-77 fab light chain (Complex from Homo sapiens)
- Spike glycoprotein (Complex from Severe acute respiratory syndrome coronavirus)
- One rbd-up state of sars-cov-2 d614g spike in complex with the sp1-77 neutralizing antibody fab fragment (650 kDa, Complex)
- Sp1-77 fab heavy chain (49 kDa, Protein from Homo sapiens)
- Sp1-77 fab light chain (23 kDa, Protein from Homo sapiens)
- Spike glycoprotein (144 kDa, Protein from Severe acute respiratory syndrome coronavirus)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Luo S, Zhang J, Kreutzberger AJB, Eaton A, Edwards RJ, Jing C, Dai HQ, Sempowski GD, Cronin K, Parks R, Ye AY, Mansouri K, Barr M, Pishesha N, Williams AC, Vieira Francisco L, Saminathan A, Peng H, Batra H, Bellusci L, Khurana S, Alam SM, Montefiori DC, Saunders KO, Tian M, Ploegh H, Kirchhausen T, Chen B, Haynes BF, Alt FW
Sci Immunol (2022) 7 pp. eadd5446-eadd5446 [ Pubmed: 35951767 DOI: doi:10.1126/sciimmunol.add5446 ]
- Sp1-77 antibody fab light chain, sp1-77 antibody fab heavy chain (Complex from Mus musculus)
- Sp1-77 antibody fab light chain (Protein from Mus musculus)
- Complex of sars-cov2 2p spike with sp1-77 antibody fab (48 kDa, Complex)
- Sars-cov2 2p spike (Complex from Severe acute respiratory syndrome coronavirus)
- Sp1-77 antibody fab heavy chain (Protein from Mus musculus)
- Sars-cov2 2p spike (Protein from Severe acute respiratory syndrome coronavirus)